LABORATORY ON THE FUNCTIONAL TOPOGRAPHY OF SMELL, VISION, TOUCH AND HEARING
This laboratory consists of two parts. First, in the gross anatomy laboratory you will identify the major sensory structures in the wet brain (left half of below tables). You will use only one hemisphere for this exercise. Your atlas will be your guide to the identification of structures. To define the course of each sensory system, begin by identifying its most peripheral structure and trace its relays centrally. Second, you will be taken to the histology laboratory where you will be shown these structures on coronal, stained sections (right half of below tables). The structures in these tables are listed in their synaptic sequence, and you should practice learning and thinking about these and all other functional systems in this sequence.
OLFACTORY SYSTEM
View the ventral surface of a hemisphere. What type of neuron (by shape) is the first neuron of the olfactory system? What part of this neuron can be considered homologous to other cranial nerves in the peripheral nervous system? What other sensory systems have the same neuron type? Find the olfactory bulb and follow caudally axons leaving it. Point out and name the structures in which these axons terminate. A symptom of temporal lobe epilepsy is the perception of disagreeable odors. Why?
CHECKLIST
| Gross Identification | Identification in Stained Sections |
| Olfactory bulb | |
| Olfactory tract | Olfactory tract |
| Lateral olfactory stria |
| Uncus Entorhinal cortex Periamygdaloid cortex Hippocampus |
© Blair H. Turner, Ph.D. 1997
SOMATOSENSORY SYSTEM
Point out the dorsal columns, and trace them to their terminations in the dorsal column nuclei. The next relay ends in the nucleus ventralis posterolateralis of the thalamus. Point it out. This relays ends in the postcentral gyrus. Trace the entire extent of this gyrus, and demonstrate its functional organization.
CHECKLIST
| Gross Identification | Identification in Stained Sections |
| Gracilis
tubercle, containing: Nucleus and fasciculus gracilis Cuneatus tubercle, containing: Nucleus and fasciculus cuneatus |
Fasciculus
and nucleus gracilis Fasciculus and nucleus cuneatus Spinal nucleus and tract of V |
| Medial
lemniscus Nuclei ventralis posterolateralis and posteromedialis Internal capsule |
|
| Postcentral gyrus | Corona radiata |
AUDITORY SYSTEM
Point out Cranial Nerve VIII. Show and name the auditory structures in which it terminates. The next relay ends in the inferior colliculus. Point it out, along with the axons leaving it (the brachium of the inferior colliculus). This relay ends in the medial geniculate. Point it out. Axons of these cells terminate in Heschl's transverse gyri. Visualize them by gently widening the posterior part of the lateral fissure. There are one or two of them. In back of them, show the planum temporale. What is its function. Trace the entire extent of the superior temporal gyrus. Where is Wernicke's speech area located?
CHECKLIST
| Gross Identification | Identification in Stained Sections |
| Cranial
Nerve VIII Dorsal cochlear nucleus |
Cranial
Nerve VIII Dorsal and ventral cochlear nuclei |
| Inferior
colliculus Brachium of the inferior colliculus |
Lateral
lemniscus Inferior colliculus |
| Medial geniculate | Medial geniculate |
| Heschl's gyri | |
| Planum temporale | |
| Area 22 | |
| Wernicke's speech area |
VISUAL SYSTEM
Almost the entire visual pathway can be seen on the intact hemisphere. Start with the optic nerve and follow the axons back to the lateral geniculate, retracting gently the temporal lobe. Notice the relationship of the pathway to the internal capsule, caudal thalamus and midbrain. Relate the structures you have just seen to the plastic embedded dissection of the visual system.
CHECKLIST
| Gross Identification | Identification in Stained Sections |
| Optic nerve | Optic nerve |
| Optic tract | Optic tract |
| Optic chiasm | Optic chiasm |
| Lateral geniculate | Lateral geniculate |
| Superior colliculus | Superior colliculus |
| Optic radiations | |
| Calcarine
fissure Upper bank (cuneus), lower visual field Lower bank (lingual gyrus),upper visual field. |